Masocare Concentrate Teat Dip / Spray Solution 2.72% w/v

Composition

For a list of full excipients see 6.1.

6.1 List of excipients

Glycerol

Sorbitol

Alcohol (C13C15) 11 Mole Ethoxylate

Sodium Hydroxide

Hydriodic Acid

Sodium Sulphate

Water Potable

3

Pharmaceutical form

Teat Dip/Teat Spray Solution.

Dark brown aqueous liquid.

3

Pharmacological properties

Pharmacotherapeutic group:

ATC Vet Code:

QD08AG03

5.1 Pharmacodynamic properties

Iodine has a powerful broad spectrum bactericidal action and is used for disinfecting unbroken skin before operation. It is also active against fungi, viruses, protozoa, cysts and spores. It is generally employed as a disinfectant for human skin application as a 2% or 2.5% solution of iodine. The germicidal activity is reduced in the presence of organic matter although the reduction is reported to be less than that observed with other halogen disinfectants.

Iodophors (such as the product) as teat disinfectants have a strong activity against a wide range of bacteria.

5.2 Pharmacokinetic properties

Absorption:

When taken by mouth, iodine preparations (which are converted to iodide) and iodides are trapped by the thyroid gland. Iodine is slightly absorbed when applied to the skin. Solutions of iodine applied to the skin should not be covered with occlusive dressings.

Distribution and Elimination:

Iodides not taken up by the thyroid are excreted mainly in the urine, with smaller amounts appearing in the faeces, saliva and sweat. They cross the placenta and are excreted in breast milk.

3

Target species

Dairy cows.

3

Indications

To be applied diluted by dipping or spraying to dairy cows' teats immediately after milking, as an aid in the control of mastitis in lactating dairy cows, and as an aid in the prevention and healing of cracked and chapped teats.

3

Dosage

Teat dipping:

Pre milking: Mix 1 part product with 9 parts of water. Fill teat dipping cup about two thirds full with the solution. Immediately before milking, dip teats of every cow making sure that the full length of the teat is immersed. Allow 15 seconds contact time, then using a single service paper towel, wipe and dry teat thoroughly, before continuing with normal milking routine. Top up with fresh solution as required. Empty and wash out cups after milking.

Post milking: Mix 1 part product with 4 parts water. Fill teat dipping cup about two thirds full with the solution and dip the teats immediately after each cow is milked. Top up the cup with fresh solution if necessary. Empty and wash out cups after milking.

Teat spraying:

Pre milking: Mix 1 part product to or 9 parts water. Immediately before milking, spray the entire surface of each teat with the solution. Allow 15 seconds contact time, then using a single service paper towel, wipe and dry teat thoroughly, before continuing with normal milking routine. Prepare a fresh solution of the diluted product daily before dipping or spraying.

Post Milking: Mix 1 part product to 4 parts. Immediately after milking, spray the entire surface of each teat with the solution. Prepare a fresh solution of the diluted product daily before dipping or spraying.

Udder Washing and cluster dipping: Mix 1 part product with 400 parts water.

3

Contraindications

None identified.

3

Adverse reactions

The product may cause an allergic reaction in some animals. In the rare case of a suspected or proven allergy in the herd, it is recommended to change to a non- iodine teat disinfectant.

3

Warnings

For external use only.

i. Special precautions for use in animals

Teat dip cups should be emptied after milking and washed before re-use. Wash and dry udders and teats before next milking.

ii. Special precautions for the person administering the veterinary medicinal product to animals

Concentrate

The following safety phrases relate to the concentrated product only, and do not apply once the product is diluted to the working solution:

Risk of serious damage to eyes.

Wear eye/face protection when preparing the dip or spray.

Diluted Working Solution

When using as a spray, avoid working in spray mist.

Avoid contact with eyes, in case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

If swallowed, seek medical advice immediately and show this container or label.

Hands and exposed skin should be washed after using this product.

Do not eat drink or smoke while using this product.

Keep away from food, drink and animal feedstuffs.

iii. Other precautions

None.

3

Use during pregnancy, lactation or lay

The product is safe to use on pregnant and lactating cows.

3

Interactions

Not to be used in conjunction with any other teat dip product.

3

Overdose

Not applicable.

3

Special warnings

None known

3

Withdrawal period

Milk: Zero hours

Meat: Zero days

3

Incompatibilities

1. Hypochlorite solutions and other oxidising agents

2 Phenolic/Soap/Pine oil disinfectants

3 Chlorhexidine teat disinfectants

4. Alkaline soaps and detergents

3

Immediate packaging

*1000 litre IBC Natural coloured drum with high density polyethylene screw cap (tamper evident seal) and dispensing tap.

* 200 litre, 60 litre opaque, white, blue, grey, green or colourless high density polyethylene drum with polypropylene co-polymer bung (2 bungs on 200 litre).

25 litre, 5 litre opaque, black, white, blue, grey, green or colourless high density polyethylene drum with high density polyethylene screw fit cap (tamper evident on 25 litres).

20L ECO II High density polyethylene 20 litre drum fitted with polyethylene screw cap (tamper-evident)

*The 200 and 1000 litre containers should not be returned for re-filling.

Not all pack sizes may be marketed.

3

Storage

Do not store above 25°C.

Store in tightly closed original container.

Protect from frost.

Store diluted product only in plastic or glass containers.

Prepare product preparations daily.

If contents freeze they must be thawed and thoroughly mixed before use. Protect from light.

3

Shelf life

Shelf life of the veterinary medicinal product as packaged for sale: 2 years.

3

Disposal of unused product

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements. To dispose of unused product to land you must have an authorisation under the Groundwater Regulations 1998.

Harmful to fish and aquatic life. Do not contaminate ponds, waterways or ditches with the product or empty container.

3

Additional information

Vm 03940/5010

9 DATE OF FIRST AUTHORISATION

20 May 1999

10 DATE OF REVISION OF THE TEXT

December 2025

Approved: 08 December 2025

3

Registration holder

Evans Vanodine International Plc

Brierley Road

Walton Summit

Preston

Lancashire

PR5 8AH

3