Johnson's Cat Flea Spray, Cutaneous Spray, Solution

Piperonyl Butoxide, Pyrethrum Extract 25%

Last verified

Veterinary medicinal product: cutaneous spray, solution. Distribution category: AVM-GSL (Veterinary Medicines Regulations 2013, Schedule 3). Active substance: Piperonyl Butoxide, Pyrethrum Extract 25%.1

In short: questions and answers

Does Johnson's Cat Flea Spray, Cutaneous Spray, Solution need a prescription?
Over the counter. As stated in the registration decision.1
Which animals is Johnson's Cat Flea Spray, Cutaneous Spray, Solution for?
Cats, Dogs.1
What is the active substance in Johnson's Cat Flea Spray, Cutaneous Spray, Solution?
Piperonyl Butoxide, Pyrethrum Extract 25%. ATCvet code: QP53AC51.13
What is the withdrawal period of Johnson's Cat Flea Spray, Cutaneous Spray, Solution according to the leaflet?
No withdrawal period is set for this drug: it is not intended for food-producing animals.3
Dispensing
Over the counter1

AVM-GSL: Authorised Veterinary Medicine - General Sale List. No prescription is needed and it may be sold by any retailer.12

Supplied without a prescription. As stated in the registration decision.

Animal species
Cats1, Dogs1
Active substance
Piperonyl Butoxide, Pyrethrum Extract 25%
ATCvet code
QP53AC513
Manufacturer
Marketing authorisation holder: Johnson's Veterinary Products Ltd

Withdrawal period

No withdrawal period is set for this drug: it is not intended for food-producing animals.3

Summary of product characteristics

Composition

Pyrethrum Extract 25%0.8% w/w
Piperonyl Butoxide1.0% w/w

For full list of excipients, see section 6.1.

6.1 List of excipients:

Kerosene Odourless

Isopropyl Alcohol

Propane/Isobutane/Butane 30 Propellant

3

Pharmaceutical form

Cutaneous spray, solution.

A clear, yellow liquid.

3

Pharmacological properties

ATC Vet code: QP53AC51

5.1 Pharmacodynamic properties:

Pyrethrins/Piperonyl Butoxide

The plant Pyrethrum is a chrysanthemate; the powdered, dried flower heads contain active principles mainly in the form of pyrethrins. Pyrethrins have insecticidal activity producing both knock-down and mortality in a range of insects, and low mammalian toxicity. Common names: Dalmatian insect powder and Persian insect powder.

Piperonyl butoxide acts as a synergist when combined with pyrethrin and prolongs its action.

5.2 Pharmacokinetic particulars:

No other information available.

3

Target species

Cats and Dogs over 12 weeks of age.

3

Indications

Insecticidal spray to kill fleas on cats and dogs over 12 weeks of age.

3

Dosage

Directions for Use: Shake can before use. Spray lightly from a distance of about 12" (30cms), all over body, commencing at tail, while brushing against lie of coat to permit spray penetration. Avoid eyes and other sensitive areas. Repeat every 3-4 days if necessary until infestation is cleared. Keep animal under observation for 30 minutes after treatment, then brush and comb to remove dead fleas.

CATS: Use Spray with caution on cats over 12 weeks of age but spray only for 3-5 seconds (NO MORE) according to size. Comb coat back into place and towel lightly to remove excess Spray. DO NOT ALLOW CAT TO GROOM UNTIL THIS HAS BEEN DONE AND COAT IS DRY. Some cats are sensitive to aerosols, in which case use a cat flea powder or cat flea collar. DOGS: This Spray may be used on dogs and puppies over 12 weeks of age, spraying small dogs for about 6 seconds, medium dogs - 9 seconds, large dogs - 14 seconds.

Fleas from pets often infest animal's basket, bedding and regular resting areas such as carpets and soft furnishings which should be treated with a suitable insecticide and vacuumed regularly. Wash or change pet bedding regularly.

3

Contraindications

Do not use on animals under 12 weeks of age or on nursing females.

3

Adverse reactions

None reported.

3

Warnings

4.5 i) Special precautions for use in animals:

For external use only.

4.5 ii) Special precautions to be taken by the person administering the medicinal product to animals:

Extremely flammable. Do not spray on a naked flame or any incandescent material.

Do not smoke when using this product.

Do not breathe spray mist and use in well ventilated area.

Avoid contact with eyes. In case of accidental eye contact, rinse with clean, fresh water. If eye irritation persists, seek medical advice.

Persons who are hypersensitive (allergic) to pyrethrum extract should handle the product with care.

Treated animals should not be allowed to sleep or play with people, particularly children, until the animal is dry.

Keep away from food and drink, including animal feeding stuffs.

Wash hands and exposed skin after use.

3

Use during pregnancy, lactation or lay

Do not use on nursing females.

3

Interactions

None reported.

3

Overdose

Hypersalivation, vomiting, diarrhoea and nervous signs are reported. Tranquilisers may be used to control CNS effects.

3

Special warnings

CATS: Spray cats for 3-5 seconds (NO MORE) according to size, then comb coat back into place and towel lightly to remove excess Spray. Do not allow cat to groom until this has been done and coat is dry. Cats should not be allowed to lick the hair of treated dogs.

DOGS & CATS:

HAZARD WARNING: Keep treated animals away from fires and other sources of heat for at least 30 minutes following spraying and until the fur is totally dry.

Remove fleas from young animals and nursing females by careful use of a flea comb.

May cause gastric irritation and nervous signs if ingested.

3

Withdrawal period

Not applicable.

3

Incompatibilities

None known.

3

Immediate packaging

Pack Size: 150ml

Container: Unlined tinplate aerosol can.

Closure: Aerosol valve assembly capable of delivering 0.85g of product per second.

3

Storage

Extremely flammable. Pressurised container: Protect from sunlight and do not expose to temperatures exceeding 50ºC. Do not pierce or burn even after use. Do not spray on a naked flame or any incandescent material. Keep away from sources of ignition – No smoking.

Do not store above 25°C.

3

Shelf life

Shelf life of the veterinary medicinal product as packaged for sale: 30 months.

3

Disposal of unused product

Harmful to fish and crustaceans. Do not contaminate aquaria and fish bowls with the product.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

3

Additional information

Vm 01759/5004

9 Date of first Authorisation:

8 October 2001

10 Date of revision of the text:

December 2025

Approved: 08 December 2025

3

Registration holder

Johnson's Veterinary Products Ltd

5 Reddicap Trading Estate

Sutton Coldfield

West Midlands B75 7DF

3

Regulations

Sources

  1. VMD Product Information Database: Johnson's Cat Flea Spray, Cutaneous Spray, Solution, 01759/5004 UK Veterinary Medicines Directorate (OGL v3.0), checked 2026-10-04 archived copy from 2026-10-04
  2. The Veterinary Medicines Regulations 2013, Schedule 3 (categories of veterinary medicinal products) UK Government, legislation.gov.uk, checked 2026-10-04 archived copy from 2026-10-04
  3. Summary of Product Characteristics: Johnson's Cat Flea Spray, Cutaneous Spray, Solution UK Veterinary Medicines Directorate, SPC of the marketing authorisation holder, checked 2026-10-04 archived copy from 2026-10-04

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